Jason Tanner

Knowledge Areas : 2020 Presidential Election, Black Lives Matter, Me Too Movement, Racism in Sports, Developmental Editing, Stylistic Editing, Copy Editing, Proofreading, Cooking, Healthy Eating, Restaurants, Snack Items, Chinese Food, American Food, Pizza, PC/Mac Games, Console Games (Xbox, PS, Nintendo, etc.), Role Playing/Fantasy, Stock Market, Literary Fiction, Science Fiction, Fantasy, Recording/Studios, Hip Hop, Retirement Planning, Growing your Savings, Personal Credit/Credit Report, Logic, Friends, Dating, Family, Twitter, Facebook, Google, Twitch.tv, Hashtag Usage, Netflix, Hulu, Disney+, Poetry, Copywriting, Fiction

Reputation Score: 170

Submit An Answer

Answers ( 3 )

  1. Sergey Zubkov 127 Community Answer

    There is only one simple active chemical in each case:

    Ibuprofen (aka Advil or Motrin) is 2-(4-Isobutylphenyl)propionic acid.

    Acetaminophen (aka Paracetamol or Tylenol or Panadol) is N-acetyl-p-aminophenol. 


    Just like the even simpler Aspirin (acetylsalicylic acid), these compounds happen to stop one or both cyclooxygenases from functioning normally. Those are the enzymes that create prostaglandins, which are a wide ranging family of chemicals that regulate fever, pain, inflammation, formation of blood clots, gastric function, etc.

    Drugs that do that are generally called NSAIDs and each of them affects some prostaglandins at slightly different rates than others, resulting in variation of effects and side-effects.


    Acetaminophen (which is not considered a true NSAID even if it does the same thing biochemically) doesn't work very well against inflammation because some of the chemicals that are formed then disable it, and also has an additional mechanism of action against TRPV1 and cannabioid receptors, which makes it better at alleviating some kinds of pain that Motrin won't do, even if it's weaker at pain management overall.


    Some recent refs:



    UTC 2021-09-21 08:14 PM 0 Comments
  2. The first part is easy. 

    Acetaminophen:  Acetominophen





    For the second part, "Google is your friend!"

    UTC 2021-09-21 03:08 PM 0 Comments
  3. Acetaminophen vs. ibuprofen

    Acetaminophen belongs to a class of drugs called analgesics. Ibuprofen belongs to the drug class called nonsteroidal anti-inflammatory drugs (NSAIDs). Both drugs decrease pain. Ibuprofen also decreases inflammation. 

    The side effects of acetaminophen and ibuprofen may differ. This is because your body breaks them down differently.

    For example, acetaminophen is broken down and removed by the liver. Acetaminophen has a warning about liver damage it can cause that can be fatal (cause death). 

    Ibuprofen, on the other hand, is removed from your body by your kidneys. Taking it for a long time can cause kidney damage and stomach bleeding. Using high doses of ibuprofen for longer than recommended can increase your risk of blood clots-heart attack-stroke 




    UTC 2021-09-21 07:38 PM 1 Comment

To answer this question, you must be logged in.

Create an account

Already have an account? Login.

By Signing up, you indicate that you have read and agree to Sage's Terms and Conditions and Privacy Policy